Examining the reservoir potential of animal species for $$\varvec{\textit{Leishmania infantum}}$$ Leishmania infantum infection
نویسندگان
چکیده
منابع مشابه
Leishmaniosis (Leishmania infantum infection) in dogs.
The authors present an overview of canine leishmaniosis due to Leishmania infantum. This protozoan is transmitted by sandflies and the disease is frequently characterised by chronic evolution. Cutaneous and visceral clinical signs appear as the infection progresses. Lymph node enlargement, emaciation and skin lesions are the main signs observed in the classical forms of the disease. Control is ...
متن کاملIncreased transmission potential of Leishmania major/Leishmania infantum hybrids.
Development of Leishmania infantum/Leishmania major hybrids was studied in two sand fly species. In Phlebotomus papatasi, which supported development of L. major but not L. infantum, the hybrids produced heavy late-stage infections with high numbers of metacyclic promastigotes. In the permissive vector Lutzomyia longipalpis, all Leishmania strains included in this study developed well. Hybrids ...
متن کاملMitochondrial peroxiredoxin functions as crucial chaperone reservoir in Leishmania infantum.
Cytosolic eukaryotic 2-Cys-peroxiredoxins have been widely reported to act as dual-function proteins, either detoxifying reactive oxygen species or acting as chaperones to prevent protein aggregation. Several stimuli, including peroxide-mediated sulfinic acid formation at the active site cysteine, have been proposed to trigger the chaperone activity. However, the mechanism underlying this activ...
متن کاملImmunologic indicators of clinical progression during canine Leishmania infantum infection.
In both dogs and humans Leishmania infantum infection is more prevalent than disease, as infection often does not equate with clinical disease. Previous studies additively indicate that advanced clinical visceral leishmaniasis is characterized by increased production of anti-Leishmania antibodies, Leishmania-specific lymphoproliferative unresponsiveness, and decreased production of gamma interf...
متن کاملVaccination with Leishmania infantum Acidic Ribosomal P0 but Not with Nucleosomal Histones Proteins Controls Leishmania infantum Infection in Hamsters
BACKGROUND Several intracellular Leishmania antigens have been identified in order to find a potential vaccine capable of conferring long lasting protection against Leishmania infection. Histones and Acid Ribosomal proteins are already known to induce an effective immune response and have successfully been tested in the cutaneous leishmaniasis mouse model. Here, we investigate the protective ab...
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ژورنال
عنوان ژورنال: Japan Journal of Industrial and Applied Mathematics
سال: 2015
ISSN: 0916-7005,1868-937X
DOI: 10.1007/s13160-015-0190-8